張婧婕

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姓名:張婧婕

出生年月:198410

最高學曆學位:博士研究生學曆,醫學博士學位

職稱:副教授

導師類型:碩士生導師

電子郵箱:jingjiezhang@btbu.edu.cn

個人簡曆

教育經曆:

20039月至20087月,北京大學,基礎醫學,學士

20089月至20127月,北京大學,藥理學,博士

201010月至20124月,美國紐約大學,聯合培養博士研究生

工作經曆:

20128月至201411月,中國食品工業(集團)公司,工程師

201412月至20188月,中國食品工業(集團)公司,高級工程師

20189月至20216月,中國農業科學院,博士後

20217月至今,雷电竞官网dota2搜哈哈电竞 ,副教授

主要研究領域

食物營養功能評價、功能性食品作用機理研究等

主要學術成果(課題、論文、獲獎、專利等)

發表的代表性論文(限10篇):

1. Yonghui Yu, Jingjie Zhang, Jing Wang, Baoguo Sun. MicroRNAs: The novel mediators for nutrient-modulating biological functions. TRENDS IN FOOD SCIENCE & TECHNOLOGY. 2021, 114: 167-175.

2. Yonghui Yu, Goutom Kumar Gaine, Linyue Zhou, Jingjie Zhang, Jing Wang, Baoguo Sun. The classical and potential novel healthy functions of rice bran protein and its hydrolysates. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION. 2021.

3. Jingjie Zhang, Yonghui Yu, Jing Wang. Protein Nutritional Support: The Classical and Potential New Mechanisms in the Prevention and Therapy of Sarcopenia. Journal of Agricultural and Food Chemistry. 2020, 68: 4098-4108.2.

4. Yonghui Yu, Jingjie Zhang, Jing Wang, Baoguo Sun. The anti-cancer activity and

potential clinical application of rice bran extracts and fermentation products. RSC Advances. 2019, 9: 18060.

5. Ruowen Zhang, Xun Che, Jingjie Zhang, Yang Li, Jingxia Li, Xu Deng, Junlan Zhu, Honglei Jin, Qinshi Zhao, Chuanshu Huang. Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation. Oncotarget. 2016 Oct 11;7(41):66689-66699.

6. Junlan Zhu, Jingjie Zhang, Haishan Huang, Jingxia Li, Yonghui Yu, Honglei Jin, Yang Li, Xu Deng, Jimin Gao, Qinshi Zhao, Chuanshu Huang. Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation. Cancer Prevention Research (Phila). 2014, 7: 1270-1281.

7. Jingjie Zhang, Guangxun Gao, Liang Chen, Jingxia Li, Xu Deng, Qin-shi Zhao, Chuanshu Huang. Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells. Oncotarget. 2014, 5: 841-852.

8. Jingjie Zhang, Guangxun Gao, Liang Chen, Xu Deng, Jingxia Li, Yonghui Yu, Dongyun Zhang, Fei Li, Min Zhang, Qinshi Zhao, Chuanshu Huang. Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis. Cancer Prevention Research (Phila). 2013,6(9):949-958.

9. Jingjie Zhang, Weiming Ouyang, Jingxia Li, Yonghui Yu, Xuejun Li, Chuanshu Huang. Suberoylanilide Hydroxamic Acid (SAHA) Inhibits EGF-induced Cell Transformation via Reduction of cyclin d1 mRNA Stability. Toxicology and Applied Pharmacology. 2012, 263: 218-224.

10. Yan Xu, Jingjie Zhang, Jing Han, Xueyang Pan, Yajun Cao, Hao Guo, Yan Pan, Yu An, Xuejun Li. Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer. Molecular Oncology. 2012, 6: 405-17.