鬱永輝

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鬱永輝

出生年月:198218

最高學曆學位: 博士研究生

職稱:  副教授

導師類型: 碩導

電子郵箱:yonghuiwh@btbu.edu.cn

個人簡曆

教育經曆:

2010.01-2012.04,美國紐約大學醫學院,環境醫學研究所,聯合培養博士生

2007.09-2012.07,武漢大學基礎醫學院,免疫學,博士(碩博連讀)

2003.09-2007.07,山東大學,生物技術,學士

工作經曆:

2018.09-至今, 雷电竞下载苹果 ,雷竞技newbee官方主赞助商 副教授

2015.08-2018.08,解放軍總醫院第一附屬醫院,全軍燒傷研究所, 副研究員

2012.08-2015.07,解放軍總醫院第一附屬醫院,全軍燒傷研究所, 博士後

主講課程

食品營養學、基礎生物化學、生理學基礎、免疫學原理與應用


主要研究領域

圍繞全穀物營養健康作用,挖掘穀物新型功能因子,探究miRNA等非編碼RNA參與新型功能因子營養健康作用的分子機製,揭示活性成分防控慢性疾病的分子機理等

主要學術成果(課題、論文、獲獎、專利等)

承擔的主要科研項目(限5項):

1. 北京市科技新星計劃,Z181100006218043miR-30a調控骨骼肌細胞自噬而介導燒傷後骨骼肌消耗的機製研究,2018.012020.12, 主持

2. 國家自然科學基金麵上項目,81471873miR-628促進燒傷後胰島素抵抗和骨骼肌消耗的機製研究,2015.012018.12, 主持

3. 北京市自然科學基金麵上項目,7172210miR-181c調控TLR4/NF-κB通路參與燒傷大鼠膿毒症發生的機製研究,2017.012019.12, 主持

4. 北京市自然科學基金青年項目,7144250miR-194參與燒傷後胰島素抵抗調控的分子機製研究,2014.012015.12, 主持

5. 中國博士後基金麵上項目,2013M533220TNFα參與燒傷後骨骼肌蛋白高分解代謝的機製研究,2013.082015.08, 主持

發表的代表性論文(限10篇):

1. Yu Yonghui#; Zhang Jingjie#; Wang Jing*; Sun Baoguo. MicroRNAs: The novel mediators for nutrient-modulating biological functions. Trends in Food Science and Technology, 2021, 114: 167-175.

2. Yu Yonghui#; Gaine, Goutom Kumar#; Zhou Linyue; Zhang Jingjie*; Wang Jing*; Sun Baoguo. The classical and potential novel healthy functions of rice bran protein and its hydrolysates. Critical Reviews in Food Science and Nutrition, 2021, 1-13.

3. Zhang Jingjie, Yu Yonghui*, Wang Jing*. Protein Nutritional Support: The Classical and Potential New Mechanisms in the Prevention and Therapy of Sarcopenia. J Agric Food Chem. 2020; 68(14): 4098–4108.

4. Yu Yonghui#, Zhang Jingjie#, Wang Jing*, Sun Baoguo. The anti-cancer activity and potential clinical application of rice bran extracts and fermentation products. RSC Advances, 2019; 9(6): 80060-18069.

5. Zhao Fen, Yu Yonghui*, Liu Wei, Liu Xinqi*, Liu Lingying, Yin Huinan. Small Molecular Weight Soybean Protein-Derived Peptides Nutriment Attenuates Rat Burn Injury-Induced Muscle Atrophy by Modulation of Ubiquitin-Proteasome System and Autophagy Signaling Pathway. J Agric Food Chem. 2018; 66(11): 2724-2734.

6. Yu Yonghui, Yang Longlong, Han Shaofang, Wu Yushou, Liu Lingying, Chang Yang, Wang Xiaoteng, Chai Jiake*. MIR-190B Alleviates Cell Autophagy and Burn-Induced Skeletal Muscle Wasting via Modulating PHLPP1/AKT/FOXO3A Signaling Pathway. Shock, 2019, 52(5): 513-521..

7. Yu Yonghui, Jin Honglei, Xu Jiheng, Gu Jiayan, Li Xin, Xie Qipeng, Huang Haishan, Li Jingxia, Tian Zhongxian, Jiang Guosong, Chen Caiyi, He Feng, Wu Xue-Ru, Huang Chuanshu. XIAP Overexpression Promotes Bladder Cancer Invasion in Vitro and Lung Metastasis in Vivo via Enhancing Nucleolin-Mediated Rho-GDIβ mRNA Stability. Int J Cancer, 2018; 142(10): 2040-2055.

8. Yu Yonghui #, Li Xiao #, Liu Lingying #, Chai Jiake *, Zhang Haijun, Chu Wanli, Yin Huinan, Ma Li, Duan Hongjie, Xiao Mengjing. miR-628 promotes burn-induced skeletal muscle atrophy via targeting IRS1. Int J Biol Sci. 2016; 12(10):1213-1224.

9. Li Xiao#, Liu Lingying#, Yang Jing#, Yu Yonghui#, Chai Jiake*, Wang Lingyan, Ma Li, Yin Huinan. Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation. Ebiomedicine. 2016; 8:72–82.ESI高被引論文

10. Yu Yonghui, Zhang Dongyun, Li Jingxia, Zhang Min, Wan Yu, Gao Jimin, Huang Chuanshu*. NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1. Oncogene, 2014; 33(8): 996-1005.